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PacBio acquires Circulomics to further improve HiFi sequencing workflows
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HiFi reads allow the accurate and simultaneous detection of single nucleotide and structural variants, paving the way for advancements in human genetics and greatly expanding the utility of SMRT Sequencing. Generating HiFi reads directly on the Sequel IIe System now has the potential to further accelerate cost-effective access to this information-rich sequencing data.
– Fritz Sedlazeck, Ph.D., Assistant Professor, Human Genome Sequencing Center at Baylor College of Medicine
My sequencing center has seen the level of interest in projects to be run on our Sequel II System increase by over 100% this year, as compared to the previous year. Many of these projects are coming from investigators and collaborators that are new to my center, they are interested in using HiFi sequencing in their research.
– Bruce Kingham, Director, Sequencing and Genotyping, University of Delaware
The Oxford Genomics Centre, the Core Facility of the Wellcome Centre for Human Genetics, is excited to invest in Pacific Biosciences' Sequel IIe, introducing their highly-accurate long-read sequencing to Oxford and beyond. This advance will drive new developments in analyses from whole viral and microbiome sequences, to complete assemblies of complex structural regions of the human genome and their epigenetic footprints.
– Prof John Todd, Centre Director & Dr David Buck, Head of High throughput Genomics, Oxford Genomics Centre, Wellcome Trust Centre for Human Genetics
It's amazing to see lower-cost human genome sequences coming from the Sequel II System approaching the quality and completeness of the human reference genome, which took billions of dollars and many years to produce.
– Jeremy Schmutz, Faculty Investigator, HudsonAlpha Institute of Biotechnology
PacBio sets the standard for long-read sequencing and this upgrade of their instrument should have high impact on genomics sciences.
– H. Steven Wiley, Judge for The Scientist 2019 Top 10 Innovations Awards
Sequence With Confidence
Using PacBio Highly Accurate Long Reads
Explore the advantages of the Sequel II and IIe Systems and SMRT Sequencing technology
Discover the Benefits for Your Research Focus
Explore the Range of Applications
Apply the versatility of SMRT Sequencing to reveal new insights